TGN46 (Trans Golgi Network 46, TGN38, TGN38 Homolog, TGN38B, TGN48, TGN51, Trans Golgi Network Integral Membrane Protein 2, Trans Golgi Network Protein 2, TGOLN2, Trans Golgi Network Protein TGN51, Trans-Golgi Network Integral Membrane Protein 1, TTGN2)

Applications: \nSuitable for use in Immunofluorescence, Flow Cytometry, Western Blot and Immunocytochemistry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

T3660-07B

Size

100ul

Applications

FC, ICC, IF, WB

Hosts

Mouse

Reactivities

Rat

Form

Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.

P Type

Mab

Purity

Ascites

Isotype

IgG1

References

This product has been used in:Horn M & Banting G Okadaic acid treatment leads to a fragmentation of the trans-Golgi network and an increase in expression of TGN38 at the cell surface. Biochem J 301 (Pt 1):69-73 (1994). <PUBMED:8037693> Stephens DJ & Banting G Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin. J Biol Chem 274:30080-6 (1999). <PUBMED:10514494>Greenfield JP et al. Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides. Proc Natl Acad Sci U S A 96:742-7 (1999). <PUBMED:9892704>Reaves B & Banting G Vacuolar ATPase inactivation blocks recycling to the trans-Golgi network from the plasma membrane. FEBS Lett 345:61-6 (1994). <PUBMED:8194602>Luzio JP et al. Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38). Biochem J 270:97-102 (1990). <PUBMED:2204342>

Additional Info

Detects Trans Golgi Network (TGN) 38 from both recombinant and endogenous rat samples. Species Crossreactivity: Crossreacts with Rat. Not yet tested in other species.