Home  >  Products  >  Th-POK, Recombinant, Human (His) (T-helper-inducing POZ/Krueppel-like factor, Zinc Finger protein 67 Homolog, ZFP67, Zinc Finger and BTB Domain-containing Protein 7B, ZBTB7B)
Th-POK, Recombinant, Human (His) (T-helper-inducing POZ/Krueppel-like factor, Zinc Finger protein 67 Homolog, ZFP67, Zinc Finger and BTB Domain-containing Protein 7B, ZBTB7B)

Th-POK, Recombinant, Human (His) (T-helper-inducing POZ/Krueppel-like factor, Zinc Finger protein 67 Homolog, ZFP67, Zinc Finger and BTB Domain-containing Protein 7B, ZBTB7B)

Cat no: 045332

Supplier: United States Biological
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Th-POK (ZFP67) is a transcription regulator that acts as a key regulator of lineage commitment of immature T cell precursors. It is necessary for commitment of CD4 lineage, while its absence causes CD8 commitment. It is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes. Sequence: Human Th-POK (aa 1-539) is fused at the C-terminus to a His-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Working aliquots are stable for up to 3 months when stored at -20 degrees C.
Catalogue number: 045332
Size: 10ug
Form: Supplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.
Purity: >90% (SDS-PAGE)
Alternative names: T-helper-inducing POZ/Krueppel-like factor, Zinc Finger protein 67 Homolog, ZFP67, Zinc Finger and BTB Domain-containing Protein 7B, ZBTB7B

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