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Th-POK, Recombinant, Mouse, (His) (T-helper-inducing POZ/Krueppel-like factor, Zinc Finger protein 67 homolog, ZFP67, Zinc Finger and BTB domain-containing protein 7B, ZBTB7B)

Cat no: 045333

Th-POK, Recombinant, Mouse, (His) (T-helper-inducing POZ/Krueppel-like factor, Zinc Finger protein 67 homolog, ZFP67, Zinc Finger and BTB domain-containing protein 7B, ZBTB7B)

Th-POK (ZFP67) is a transcription regulator that acts as a key regulator of lineage commitment of immature T cell precursors. It is necessary for commitment of CD4 lineage, while its absence causes CD8 commitment. It is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes.\n\nSequence:\nMouse Th-POK (aa 1-544) is fused at the C-terminus to a His-tag.\n\nStorage and Stability:\nShort-term Storage: +4 degrees C\nLong-term Storage: -20 degrees C\nWorking aliquots are stable for up to 3 months when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

045333

Size

10ug

Form

Supplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.

Purity

>90% (SDS-PAGE)

Alternative Names

T-helper-inducing POZ/Krueppel-like factor, Zinc Finger protein 67 homolog, ZFP67, Zinc Finger and BTB domain-containing protein 7B, ZBTB7B

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