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Thielavin A

Cat no: T5006-50

Thielavin A

The fungal metabolite thielavin A and its relatives are glucose-6-phosphatase inhibitors. The three benzoic acid units are essential for inhibition. Thielavin A was originally isolated as a inhibitor of prostaglandin biosynthesis. The closely related thielavin B is a telomerase and cell wall transglycosylation inhibitor.\n\nPurity: >94% by HPLC\n\nSolubility: Soluble in methanol and DMSO.\n\nRelated to: Thielavin B

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SPECIFICATIONS

Catalog Number

T5006-50

Size

500ug

Purity

>94% by HPLC\n

References

1. Thielavins as glucose-6-phosphatase (G6Pase) inhibitors: producing strain, fermentation, isolation, \nstructural elucidation and biological activities. Sakemi S. et al. J. Antibiot. 2002, 55, 941. \n2. Inhibition of telomerase activity by fungus metabolites, CRM646-A and thielavin B. Togashi K. et al. \nBiosci. Biotechnol. Biochem. 2001, 65, 651. \n3. Screening systems for detecting inhibitors of cell wall transglycosylation in Enterococcus. Cell wall \ntransglycosylation inhibitors in Enterococcus. Mani N. et al. J. Antibiot. 1998, 51, 471. \n4. The structures of thielavins A, B and C. Prostaglandin synthetase inhibitors from fungi. Kitahara N. et al. \nJ. Antibiot. 1983, 36, 599.

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Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

More info

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

More info
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