Thioguanine (2C2) Antibody

Cat no: 250360

Supplier: ABBIOTEC

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Description
Additional Information

Thioguanine is a purine analogue used in cancer chemotherapy. It is the 6-thione analogue of the endogenous 6-OH purine base guanine. In the cell thioguanine is converted to the ribonucleotides: 6-thioguanosine-5'-phosphate and 6-thioinosine-5'-phosphate. These fraudulent nucleotides produce their cytoto, Xenopus/Amphibian,ic effects by several mechanisms, e.g. inhibitory action on de novo purine synthesis, and may themselves be incorporated into DNA. Thioguanine has a molecular weight of 167 Da. This antibody is specific for thioguanine. Cross-reactivity is seen with 6-(methylthio)purine, but not with various other thioguanine analogs.

Catalogue number:	250360
Size:	0.2 mg
Accession:	P00492
Antigen:	S-substituted thioguanine linked to PPD (2)
Format:	Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2a/l
Clonality:	2C2
Additional info:	HGPRT; HGPRTase