Thioguanine (5B2) Antibody

Cat no: 250349

Supplier: ABBIOTEC

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Description
Additional Information

Thioguanine is a purine analogue used in cancer chemotherapy. It is the 6-thine analogue of the endogenous 6-OH purine base guanine. In the cell thioguanine is converted to the ribonucleotides: 6-thioguanosine-5'-phosphate and 6-thioinosine-5'-phosphate. These fraudulent nucleotides produce their cytoto, Xenopus/Amphibian,ic effects by several mechanisms, e.g. inhibitory action on de novo purine synthesis, and may themselves be incorporated into DNA. Thioguanine has a molecular weight of 167 Da. This antibody is specific for thioguanine. Crossreactivity is seen with a variety of thioguanine analogs, e, Xenopus/Amphibian,cept with 6-(methylthio)purine, 6-(methylthio)purine riboside, 6-thio, Xenopus/Amphibian,anthine and 2-amino-8-phenyl-6-purinethione.

Catalogue number:	250349
Size:	0.2 mg
Accession:	P00492
Antigen:	9-substituted thioguanine linked to PPD (2)
Format:	Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2a/k
Clonality:	5B2
Additional info:	HGPRT; HGPRTase