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Thioredoxin, Recombinant Human (ADF)

Thioredoxin, Recombinant Human (ADF)

Cat no: T5010-13

Supplier: United States Biological
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Recombinant Human TRX/ADF is produced by DNA recombinant procedure in E. coli as an intracellular protein. In the search for a possible mechanism of interleukin 2 receptor a-chain (IL-2Ra)/p55 (Tac) induction in adult T cell leukemia (ATL), a soluble factor responsible for this receptor abnormality was discovered by Teshigawara et al. The factor called ATL-derived factor (ADF) enhanced the IL-2Ra expression on some lymphocytes. After gene cloning, ADF proved to be the human homologue of dithiol-related reducing enzyme thioredoxin. Application: Suitable for use as medium component as anti-oxidant, diagnosis of Sjogren
Catalogue number: T5010-13
Size: 100ug
Form: Supplied as lyophilized powder.
Purity: Purified
References: 1. Buchanan BB, Schurmann P, Decottignies P, Lozano RM: Arch. Biochem. Biophys., 314, 257-260 (1994) 2. Mitsui A, Hirakawa T. Yodoi J: Biochem. Biophys. Res Commun., 186, 1220-1226 (1992) 3. Teshigawara K, Maeda M, Nishino K, et al: J. Mol. Ccell. Immun., 2, 17-26 (1985) 4. Uchiyama T, Yodoi J: Adult T Cell Leukemia and Related Diseases. Medical Intelligence Unit (1995) (Springer-Verlag) 5. Saito I, Shimuta M, Terauchi K, Tsubota K, Yodoi J, Miyasaka N: Arthritis & Rheumatism, 39, 773-782 (1996)

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