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THP (V378) pAb

THP (V378) pAb

Cat no: BS2944

Supplier: Bioworld Technology, Inc.
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Tamm-Horsfall glycoprotein (also referred to as uromodulin or THP) is the most abundant protein found in normal urine. THP is expressed on the luminal surface of the membrane with the glycosyl phosphatidylinositol (GPI) anchor and excreted in urine at a rate of 50-100 mg per day. THP, uropontin and nephrocalcin are the three known urinary glycoproteins that affect the formation of calcium-containing kidney stones. THP is synthesized by kidney epithelial cells and is believed to play important and diverse roles in the urinary system,including renal water balance, immunosuppression, urinary stone formation and inhibition of bacterial adhesion. THP is nontoxic and blocks early events required for normal T cell proliferation in vitro.
Catalogue number: BS2944
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P07911
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 341-390 of Human THP.
Species: THP (V378) pAb detects endogenous levels of THP protein.
Molecular weight: ~ 70 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Uromodulin; Tamm-Horsfall urinary glycoprotein; THP; UMOD
Additional info: For research use only, not for use in diagnostic procedure.

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