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Thrombin Antithrombin III (TAT) Complexes, Human, BioAssay(TM) ELISA Kit (Antibodies only)

Cat no: T5045-65

Thrombin Antithrombin III (TAT) Complexes, Human, BioAssay(TM) ELISA Kit (Antibodies only)

Thrombin is a key clot promoter. It is an enzyme that presides over the conversion of a fibrinogen to fibrin. The coagulation cascade, is a series of proenzyme-enzyme conversions. Coagulation starts when a vessel is wounded. A vessel is wrapped in a layer that is full of cells containing Tissue Factor (TF). After injury, TF is exposed to blood, it binds with factor VIIa to form the first enzyme: TF:VIIa. This activates factor X to Xa, which in turn forms thrombin. Antithrombin III is a protein that regulates and prevents blood clotting. Antithrombin III is a potent inhibitor of the coagulation cascade. It is a non

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SPECIFICATIONS

Catalog Number

T5045-65

Size

1Kit

Applications

ELISA

Reactivities

Hum

References

1. Pelzer, H., et al., Thrombosis and Haemostasis 59: 101-106 (1988). 2. Butler, J.E., et al., Federation Proceedings 46: 2548-2556 (1987). 3. Harlow, E. & Lane, D.; Detecting and Quantitating Antigens using the Two-Antibody Sandwich Assay, in Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory (1988) 580.

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