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Thrombopoietin, Recombinant, Mouse (TPO, Megakaryocyte Colony Stimulating Factor, c-MPL Ligand, MGDF)

Cat no: 142988

Thrombopoietin, Recombinant, Mouse (TPO, Megakaryocyte Colony Stimulating Factor, c-MPL Ligand, MGDF)

Thrombopoietin (TPO) is a growth factor that is produced by the liver and kidney. TPO acts through the TPO receptor to promote megakaryocytematurationanddifferentiation,whichleadstotheproductionofplatelets.\n\nSource:\nRecombinant protein corresponding to 174aa from mouse TPO expressed in E.coli. \n\nMolecular Weight: \n~18.7kD\n\nEndotoxin:\n(same/less than)1EU/ug (LAL) \n\nBiological Activity:\nThe activity is determined by the dose-dependent stimulation of MO7e cells and is typically <1ng/ml.\n\nAA Sequence:\nSPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF\n\nStorage and Stability: \nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

142988

Size

2ug

Form

Supplied as a lyophilized powder in 10mM Na2PO4, pH 7.5. Reconstitute with sterile H20.

Purity

~97% (Reducing and non-reducing SDS-PAGE)

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