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THSD1 (Thrombospondin Type-1 Domain-containing Protein 1, Transmembrane Molecule with Thrombospondin Module, Tmtsp) (PE)

Cat no: T5101-09A

THSD1 (Thrombospondin Type-1 Domain-containing Protein 1, Transmembrane Molecule with Thrombospondin Module, Tmtsp) (PE)

THSD1 (thrombospondin type 1 domain-containing protein 1; also TMTSP) is a 90-100kD type I transmembrane protein that is reminiscent of Unc5h proteins. It is expressed on embryonic endothelial and hematopoietic stem cells and may be involved in cell-cell interactions. Mature human THSD1 is 827aa in length. It contains a 388aa extracellular domain (ECD; aa25-412) and a 418aa cytoplasmic region (aa434-851). The ECD possesses three Ig-like domains (aa156-316) and one TSP type-1 domain (aa340-393). There is one potential alternate start site at Met380 and two splice variants, one of which shows a deletion of aa341-393 and a second that shows a 36aa substitution for aa394-851, generating a soluble form. Over aa25-361, human THSD1 is 76% identical to mouse THSD1.\n\nApplications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilutions:\nOptimal dilutions to be determined by the researcher.\n\nHybridoma:\nMyeloma with B cells from Balb/c mice. \n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

T5101-09A

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in sodium chloride, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG1

Additional Info

Recognizes human THSD1. Species sequence homology: mouse (76%).

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