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Thyroid Hormone Receptor alpha1, alpha2 (Thyroid Hormone Receptor alpha, THRA, THRA1, THRA2, AR7, c-erbA-1, ERBA1, c-erbA-alpha, ERBA, EAR7, EAR-7, ERB-T-1, MGC000261, MGC43240, Nuclear Receptor Subfamily 1 Group A Member 1, NR1A1, V-erbA-related Protein

Cat no: T5348-99G

Thyroid Hormone Receptor alpha1, alpha2 (Thyroid Hormone Receptor alpha, THRA, THRA1, THRA2, AR7, c-erbA-1, ERBA1, c-erbA-alpha, ERBA, EAR7, EAR-7, ERB-T-1, MGC000261, MGC43240, Nuclear Receptor Subfamily 1 Group A Member 1, NR1A1, V-erbA-related Protein

Thyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TR alpha and TR beta, have been mapped to Human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3

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SPECIFICATIONS

Catalog Number

T5348-99G

Size

500ul

Applications

IHC

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Prc

Form

Supplied as a liquid in 0.05% sodium azide.

P Type

Pab

Purity

Serum

Isotype

IgG

Additional Info

Recognizes human TR a1/a2. Species Crossreactivity: mouse, porcine and rat.

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