Thyroid Hormone Receptor beta Antibody

Cat no: 253230

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

Thyroid hormones are essential for development of the central nervous system. Deficits in these hormones during development affect cognitive functions as learning and memory. Thyroid hormones e, Xenopus/Amphibian,ert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TRb1 and TRb2. TRa1, TRb1 and TRb2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain.

Catalogue number:	253230
Reactivities:	Human, Mouse, Rabbit
Applications:	Western Blot
Size:	0.1 ml
Accession:	P10828
Antigen:	KLH-conjugated peptide encompassing a sequence within the N-term region of human thyroid hormone receptor, b-isotype.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	2386
Additional info:	Thyroid hormone receptor beta; Nuclear receptor subfamily 1 group A member 2; c-erbA-2; c-erbA-beta; THRB; ERBA2; NR1A2; THR1