TIGAR Antibody

Cat no: 250533

Supplier: ABBIOTEC

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Description
Additional Information

TIGAR is a probable fructose-biphosphatase that lowers cellular levels of fructose 2,6-bisphosphate, thus blocking glycolysis and directing the pathway into the pentose phosphate shunt. TIGAR protects cells against reactive o, Xenopus/Amphibian,ygen species. It is rapidly up-regulated by p53, and protects against p53-induced apoptosis. TIGAR is phosphorylated upon DNA damage,Porcinerobably by ATM or ATR.

Catalogue number:	250533
Reactivities:	Human, Mouse
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q9NQ88
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TIGAR.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit IgG
Additional info:	Probable fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator; TIGAR; C12orf5