TIMM50, NT (TIMM50, TIM50, Mitochondrial import inner membrane translocase subunit TIM50) (Biotin)

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

042846-Biotin

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Conjugates

Biotin

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Biotin.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :\nXu, H., et al. BMC Cell Biol. 6 (1), 29 (2005) :\nGuo, Y., et al. J. Biol. Chem. 279(23):24813-24825(2004)\nYuryev, A., et al. Genomics 81(2):112-125(2003)\nYamamoto, H., et al. Cell 111(4):519-528(2002)

Additional Info

Human

Alternative Names

TIMM50, TIM50, Mitochondrial import inner membrane translocase subunit TIM50