Home  >  Products  >  TL1A (TNF Ligand-related Molecule 1, TL1, MGC129934, MGC129935, Tumor Necrosis Factor Ligand Superfamily Member 15, TNFSF15, Vascular Endothelial Cell Growth Inhibitor, VEGI, VEGI192A)
TL1A (TNF Ligand-related Molecule 1, TL1, MGC129934, MGC129935, Tumor Necrosis Factor Ligand Superfamily Member 15, TNFSF15, Vascular Endothelial Cell Growth Inhibitor, VEGI, VEGI192A)

TL1A (TNF Ligand-related Molecule 1, TL1, MGC129934, MGC129935, Tumor Necrosis Factor Ligand Superfamily Member 15, TNFSF15, Vascular Endothelial Cell Growth Inhibitor, VEGI, VEGI192A)

Cat no: T8038-05E

Supplier: United States Biological
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Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3:TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-?B activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Mouse lung cell lysates. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8038-05E
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified
References: 1. Chinnayan AM, O
Additional info: Recognizes human TL1A. Species Crossreactivity: mouse.

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