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TLR13 (Toll Like Receptor 13, Toll-like Receptor 13)

TLR13 (Toll Like Receptor 13, Toll-like Receptor 13)

Cat no: T8051-30G

Supplier: United States Biological
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TLR13, also known as Toll like receptor 13, is a member of the Toll-like receptor (TLR) family of transmembrane proteins comprised of multiple copies of leucine rich repeats in the extracellular domain and a TIR domain. The exact function of this 991aa containing protein is yet unknown, but reports suggest that it is closely related to TLR3 and participates in the innate immune response to microbial agents. TLR13 binds to and acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and inflammatory response. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8051-30G
Reactivities: Mouse, Rat
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Wu, H. et al. Endocrinology. 149:4402-4412 (2008). 2. Shi, Z. et al. J. Biol. Chem. 284:20540-20547 (2009).
Additional info: Recognizes mouse TLR13. Species Crossreactivity: rat.

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