TLR2 (2D6) Antibody

Cat no: 252950

Supplier: ABBIOTEC

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Description
Additional Information

TLR2 (Toll-like receptor 2) participates in the innate immune response to microbial agents. Toll-like receptor family (TLR) has a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMP) that are e, Xenopus/Amphibian,pressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Toll-line receptor 2 (TLR2) cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. TLR2 acts via MYD88 and TRAF6 to lead to NFkB activation, cytokine secretion and inflammatory response. TLR2 is highly e, Xenopus/Amphibian,pressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, in lymph node and in spleen. Genetic variations in TLR2 are associated with susceptibility to leprosy, due to Mycobacterium leprae infection.

Catalogue number:	252950
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	O60603
Antigen:	Purified recombinant fragment of human TLR2 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	2D6
Additional info:	Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD282; TLR2; TIL4