TLR2 Antibody

Cat no: 251110

Supplier: ABBIOTEC

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Description
Additional Information

Toll-like receptor family (TLR) has a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMP) that are e, Xenopus/Amphibian,pressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Toll-line receptor 2 (TLR2) cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. TLR2 acts via MYD88 and TRAF6 to lead to NFkB activation, cytokine secretion and inflammatory response. TLR2 is highly e, Xenopus/Amphibian,pressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, in lymph node and in spleen. Genetic variations in TLR2 are associated with susceptibility to leprosy, due to Mycobacterium leprae infection.

Catalogue number:	251110
Reactivities:	Human, Mouse, Porcine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	O60603
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TLR2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD282; TLR2; TIL4