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TLR3 pAb

Cat no: BS6749

TLR3 pAb

Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated Toll-like receptors (TLR). TLR3 is highly expressed in placenta and pancreas, and is limited to the dendritic subpopulation of leukocytes. TLR3 recognizes dsRNA associated with viral infection and induces activation of NFkB and production of type I interferons, which suggests that it may play a role in host defense against viruses. TLR6 is highly homologous to TLR1, sharing greater than 65% sequence identity. Like other members of TLR family, TLR6 induces NFkB signaling upon activation.

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SPECIFICATIONS

Catalog Number

BS6749

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human TLR3.

Species

TLR3 pAb detects endogenous levels of TLR3 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

O15455

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~108 kDa

Alternative Names

CD283; CD283 antigen; IIAE2; TLR 3; Tlr3; TLR3; Toll Like Receptor 3; Toll-like receptor 3;

SUPPLIER INFO

Bioworld Technology, Inc.

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