Species: mouse - male, 11 to 13 days old
Strain: BALB/c nu/+
Receptor: luteinizing hormone (LH); epidermal growth factor(EGF); androgen; estrogen; progesterone
Production: prostaglandin F2a
Histopathology: normal
Note: the TM3 cell line responds to LH with an increase in cAMP production, but does not respond to follicle stimulating hormone (FSH); the maintenance of responsiveness to LH is dependent upon serum lot; in the presence of LH, the cells are capable of metabolizing cholesterol; tested and found negative for ectromelia virus (mousepox)