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TNAP / ALPL pAb

TNAP / ALPL pAb

Cat no: BS6134

Supplier: Bioworld Technology, Inc.
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Alkaline phosphatases (AP) are glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+ metallated glycoproteins that catalyze the hydrolysis of phospho-monoesters into an inorganic phosphate and an alcohol. There are at least four distinct but related alkaline phosphatases: intestinal (IAP), placental (PLAP), placental-like (ALP-1 or GCAP) and tissue non-specific (TNAP). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. TNAP is widely expressed in liver, kidney, bone, stomach and colon, and is therefore referred to as the tissue non-specific form of AP. TNAP, in conjuntion with plasma cell membrane glycoprotein-1, function in bone mineralization; however, mice that lack a functional form of TNAP show normal skeletal development.
Catalogue number: BS6134
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P05186
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human TNAP / ALPL.
Species: ALPL pAb detects endogenous levels of ALPL protein.
Molecular weight: ~ 57 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Akp2; Alkaline phosphatase intestinal; Alkaline phosphatase intestinal precursor; Alkaline phosphatase liver/bone/kidney; Alkaline phosphatase placental; Alkaline phosphatase placental like 2; Alkaline phosphatase placental like; Alkaline phosphatase placental type; Alkaline phosphomonoesterase; ALP 1; ALP; ALP I; ALP L; ALP P; ALPG; ALPI; ALPL; ALPP; ALPPL; ALPPL2; AP TNAP; FLJ40094; GCAP; Germ cell alkaline phosphatase; Glycerophosphatase; HOPS; IAP; Intestinal alkaline phosphatase; Kasahara i
Additional info: For research use only, not for use in diagnostic procedure.

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