TNF-R2 Antibody

Cat no: 250107

Supplier: ABBIOTEC

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Description
Additional Information

Tumor necrosis factor receptor 2 (TNF-R2) is a high-affinity receptor for TNF-alpha and a low-affinity receptor for lymphoto, Xenopus/Amphibian,in-alpha. TNF-R2 has two isoforms produced by alternative splicing: a cell membrane and a secreted form. The latter blocks TNF-alpha-induced apoptosis, which suggests that this isoform regulates TNF-alpha function by antagonizing its biological activity. A soluble fragment of TNF-R2 (Enbrel, Immune, Xenopus/Amphibian, and Wyeth-Ayerst) is used as treatment of moderate and severe rheumatoid arthritis. This antibody recognizes human TNF-R2 in ELISA and flow cytometry.

Catalogue number:	250107
Reactivities:	Human
Applications:	Flow Cytometry
Size:	0.1 mg
Accession:	P20333, NP_001057
Antigen:	Recombinant soluble human TNF-R2-Fc fusion protein
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	mouse IgG2a
Clonality:	KT30
Additional info:	Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; p75; p80 TNF-alpha receptor; CD120b antigen; Etanercept; Tumor necrosis factor-binding protein 2; TNFRSF1B; TNFBR, TNFR2