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Tnfsf14, Recombinant, Mouse (Tumor Necrosis Factor Ligand Superfamily Member 14, CD258, Light, HVEML, HVEM-L)

Cat no: 149707


Supplier: United States Biological
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LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant mouse LIGHT is a 20.1kD protein containing 183aa. Source: Recombinant protein corresponding to mouse LIGHT, expressed in E.coli. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 149707
Size: 5ug
Form: Supplied as a lyophilized powder.
Purity: ~98% (SDS-PAGE and HPLC)

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