TNK1 (1B5G) Antibody

Cat no: 252782

Supplier: ABBIOTEC

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Description
Additional Information

TNK1 (Tyrosine kinase, non-receptor, 1) is a nonreceptor tyrosine kinase (NRPTK). These kinases, like members of the SRC (MIM 190090) and JAK (see MIM 147795) families,Mouse,ediate intracellular signaling downstream of receptor activation. Tnk1 is a ubiquitously e, Xenopus/Amphibian,pressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.

Catalogue number:	252782
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	Q13470
Antigen:	Purified recombinant fragment of TNK1(aa451-560) e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	1B5G3;3F11H6
Additional info:	Non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1; TNK1