TOP2B Antibody

Cat no: 252228

Supplier: ABBIOTEC

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Description
Additional Information

DNA topoisomerase 2-beta (TOP2B) controls topological states of DNA by transient breakage and subsequent rejoining of DNA strands. TOP2B makes double-strand breaks. TOP2B is indirectly involved in vitamin D-coupled transcription regulation via its association with the WINAC comple, Xenopus/Amphibian,, a chromatin-remodeling comple, Xenopus/Amphibian, recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Eukaryotic topoisomerase I and II can rela, Xenopus/Amphibian, both negative and positive supercoils, whereas prokaryotic enzymes rela, Xenopus/Amphibian, only negative supercoils.

Catalogue number:	252228
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q02880
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TOP2B.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	TOP2B; DNA topoisomerase 2-beta; DNA topoisomerase II, beta isozyme; TOP2B