Home  >  Products  >  Topoisomerase I (DNA Topoisomerase 1, DNA Topoisomerase I, NUP98 Fusion Gene, TOP 1, TOP1, TOP-1, TOP I, TOPI, TOP-I, Topoisomerase (DNA) I, Topoisomerase 1, Topoisomerase1, Topoisomerase-1, Topoisomerase-I, Type I DNA Topoisomerase)
Topoisomerase I (DNA Topoisomerase 1, DNA Topoisomerase I, NUP98 Fusion Gene, TOP 1, TOP1, TOP-1, TOP I, TOPI, TOP-I, Topoisomerase (DNA) I, Topoisomerase 1, Topoisomerase1, Topoisomerase-1, Topoisomerase-I, Type I DNA Topoisomerase)

Topoisomerase I (DNA Topoisomerase 1, DNA Topoisomerase I, NUP98 Fusion Gene, TOP 1, TOP1, TOP-1, TOP I, TOPI, TOP-I, Topoisomerase (DNA) I, Topoisomerase 1, Topoisomerase1, Topoisomerase-1, Topoisomerase-I, Type I DNA Topoisomerase)

Cat no: T8064-99A

Supplier: United States Biological
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Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Extract of A231 human kidney cells. Cellular Localization: Cytoplasmic and Nuclear Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T8064-99A
Reactivities: Human
Hosts: Mouse
Applications: Western Blot
Size: 50ul
Form: 15mM Sodium Azide; 0.01M PBS. pH 7.4
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
References: Champoux JJ DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem 70:369-413 (2001). Takahashi H et al. Monoclonal antibodies against topoisomerase I suppressed DNA relaxation and HIV-1 cDNA synthesis. Hybridoma 19:331-4 (2000). Froelich-Ammon SJ & Osheroff N Topoisomerase poisons: harnessing the dark side of enzyme mechanism. J Biol Chem 270:21429-32 (1995).
Additional info: Species Crossreactivity: Crossreacts with Human.

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