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Topoisomerase II (DNA) beta (TOP IIB, Top2 beta, Antigen MLAA 44, U937-associated Antigen)

Topoisomerase II (DNA) beta (TOP IIB, Top2 beta, Antigen MLAA 44, U937-associated Antigen)

Cat no: T8065-21E

Supplier: United States Biological
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Topoisomerase II beta plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is present ubiquitously in normal cells and is unregulated in tumors and proliferating cells. Topoisomerase II beta is also implicated in drug resistance of tumor cells. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Tonsil Cellular Localization: Nuclear Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T8065-21E
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 500ul
Form: Supplied as a liquid in 10mM PBS, BSA. pH 7.4, 0.1% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Detects a band at approximately 300kD.

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