TPM4, NT (TPM4, Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4)

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].\n\nApplications:\nSuitable for use in Western Blot, Flow Cytometry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nFlow Cytometry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

043160

Size

200ul

Applications

ELISA, FC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Martins-de-Souza, D., et al. J Psychiatr Res 44(14):989-991(2010)\nVlahovich, N., et al. Cell Motil. Cytoskeleton 65(1):73-85(2008)\nMontesano Gesualdi, N., et al. Free Radic. Res. 40(5):467-476(2006)\nHossain, M.M., et al. J. Biol. Chem. 280(51):42442-42453(2005)\nBruneel, A., et al. Proteomics 5(15):3876-3884(2005)

Additional Info

Human

Alternative Names

TPM4, Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4