Home  >  Products  >  TRAC-1 (T cell RING Activation Protein 1, TRAC 1, E3 Ubiquitin Protein Ligase RNF125, FLJ20456, MGC21737, Ring Finger Protein 125, RNF125, T-cell Ring Protein Identified in Activation Screen)
TRAC-1 (T cell RING Activation Protein 1, TRAC 1, E3 Ubiquitin Protein Ligase RNF125, FLJ20456, MGC21737, Ring Finger Protein 125, RNF125, T-cell Ring Protein Identified in Activation Screen)

TRAC-1 (T cell RING Activation Protein 1, TRAC 1, E3 Ubiquitin Protein Ligase RNF125, FLJ20456, MGC21737, Ring Finger Protein 125, RNF125, T-cell Ring Protein Identified in Activation Screen)

Cat no: T8169-32

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
TRAC-1 is a 232aa protein containing an N-terminal RING-type zinc finger domain. It functions as a positive regulator in the T-cell receptor signaling pathway, thus leading to T-cell activation. It mediates ubiquitination and subsequent proteasomal degradation of target proteins. TRAC-1 is expressed in lymphoid tissues, including bone marrow, spleen, thymus as well as in other tissues. It is predominantly expressed in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8169-32
Reactivities: Human, Non-Human Primate
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Serum
Alternative names: EC=6.3.2.-
References: 1. Zhao, H. et al. J. Immunol. 174:5288-5297 (2005).
Additional info: Recognizes human TRAC-1. Species Crossreactivity: chimpanzee, monkey. Species sequence homology: bovine, equine, mouse, rat, canine.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave