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TRAcP (Tartrate-resistant Acid Phosphatase, Purple Acid Phosphatase, Acid Phosphatase 5)

TRAcP (Tartrate-resistant Acid Phosphatase, Purple Acid Phosphatase, Acid Phosphatase 5)

Cat no: T8266-95A

Supplier: United States Biological
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Serum tartrate-resistant acid phosphatase exists as two isoforms (TRAcP5a and 5b). They are derived by differential-posttranslational processing of a common gene. Serum TRAcP5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP5b is produced from osteoclasts and elevated during bone resorption. In addition, this antibody labels hairy leukemia cells with high degree of sensitivity and specificity. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.5-1ug/ml Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8266-95A
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 25ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by affinity chromatography.
References: 1. Janckila AJ, et al. 1995. Blood 85:2839. 2. Janckila AJ, et al. 1996. J. of Histochem. and Cytochem. 44:235. 3. Janckila AJ, et al. 2005. J. Leukocyte Biol. 77:209.
Additional info: Recognizes human TRAcP. Reacts with both TRAcP 5a and 5b isoforms. Species Crossreactivity: mouse and rat

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