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TRAIL-3, NT (Death Ligand 3-like; Tumor Necrosis Factor-related Apoptosis-inducing Ligand)

TRAIL-3, NT (Death Ligand 3-like; Tumor Necrosis Factor-related Apoptosis-inducing Ligand)

Cat no: T8180-10

Supplier: United States Biological
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Death ligand 3-like, also called tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), is one of the several members of the tumor necrosis factor TNF) gene superfamily that induce apoptosis through engagement of death receptors (DRs). By interacting with two receptors, named DR4 (death receptor 4 or TRAIL-R1) and DR5 (TRAIL- R2), to initiate the formation of TRAIL DISC, thus induce the apoptosis. In addition, three other receptors, DcR1 (TRAIL-R3), DcR2 (TRAIL-R4), and the soluble TNFR family member osteoprotegerin (OPG) can bind to the TRAIL to act as
Catalogue number: T8180-10
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Pitti RM, et al. J. Biol. Chem. 271: 12687-12690 2. Wiley SR, et al. Immunity 3: 673-682 3. LeBlanc, HN., et al. Cell Death and Differentiation (2003) 10, 66-75.
Additional info: Recognizes zebrafish TRAIL-3.

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