TRAIL (TNF Related Apoptosis Inducing Ligand, TNF-related Apoptosis-inducing Ligand TRAIL, Apo 2 Ligand, Apo2 Ligand, Apo-2 Ligand, Apo 2L, Apo2L, Apo-2L, CD253, CD253 Antigen, Protein TRAIL, TL2, Tumor Necrosis Factor (Ligand) Superfamily Member 10, TNFS

Applications: \nSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry (Fr). Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nCellular Localization: Cell Membrane\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

T8180-01C

Size

1ml

Applications

IHC, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

0.1% Sodium Azide 0.2% Gelatin, PBS

P Type

Pab

Purity

Serum

Isotype

IgG

References

Wajant H et al. TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy. Apoptosis 7:449-59 (2002). <PUBMED:12207178>Nagane M et al. The potential of TRAIL for cancer chemotherapy. Apoptosis 6:191-7 (2001). <PUBMED:11388668>Phillips TA et al. TRAIL (Apo-2L) and TRAIL receptors in human placentas: implications for immune privilege. J Immunol 162:6053-9 (1999). <PUBMED:10229846>Gura T How TRAIL kills cancer cells, but not normal cells. Science 277:768 (1997). <PUBMED:9273698>Pitti RM et al. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271:12687-90 (1996). <PUBMED:8663110>

Additional Info

Species Crossreactivity: Crossreacts with Human, Rat and Mouse.