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trans-Ned-19

Cat no: 018051


Supplier: United States Biological
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trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells. Form: Dark Yellow Solid Melting Point: 168-173 degrees C Solubility: Methanol
Catalogue number: 018051
Size: 5mg
Form: Dark Yellow Solid
Alternative names: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;
References: Rosen, D. et al.: J. Biol. Chem., 284, 34930 (2009); Naylor, E. et al.: Nat. Chem. Biol., 5, 220 (2009); Thai, T.L. et al.: Am. J. Physiol. Renal Physiol., 297, F510 (2009);

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