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Transcription Factor 4, T-cell Specific, HMG-box (TF4, TF7L2, Transcription Factor 7-like 2)

Cat no: T8195-35A


Supplier: United States Biological
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TCF4 (transcription factor 4) is otherwise known as TF7L2, a basic helix-loop-helix (bHLH) domain-containing nuclear protein and member of the Tcf/Lef family, which interacts with beta-catenin to mediate Wnt signalling, acting as a transcriptional activator in cell development processes. Applications: Suitable for use in Immunofluorescence, Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilution: Immunofluorescence: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8195-35A
Reactivities: Human
Hosts: Rabbit
Applications: Immunofluorescence, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Valenta, T. et al. (2006) HIC1 attenuates Wnt signaling by recruitment of TCF-4 and Beta-catenin to the nuclear bodies. EMBO J. 25: 2326-2337.
Additional info: Recognizes human transcription factor 4.

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