Home  >  Products  >  Transcription Factor AP-2 beta (Transcription Factor AP 2 beta, Transcription factor AP2 beta, TFAP2B, Activating Enhancer Binding Protein 2 beta, AP2 beta, AP2beta, AP2-beta, AP2B, AP-2B, AP2-B, MGC21381, OTTHUMP00000039925)
Transcription Factor AP-2 beta (Transcription Factor AP 2 beta, Transcription factor AP2 beta, TFAP2B, Activating Enhancer Binding Protein 2 beta, AP2 beta, AP2beta, AP2-beta, AP2B, AP-2B, AP2-B, MGC21381, OTTHUMP00000039925)

Transcription Factor AP-2 beta (Transcription Factor AP 2 beta, Transcription factor AP2 beta, TFAP2B, Activating Enhancer Binding Protein 2 beta, AP2 beta, AP2beta, AP2-beta, AP2B, AP-2B, AP2-B, MGC21381, OTTHUMP00000039925)

Cat no: T8195-52E2

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
AP2-beta is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes during early development. AP-2 factors bind to the consensus sequence 5\'-GCCNNNGGC-3\' and activate genes involved in large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes. AP2-beta appears to be required for normal face and limb development and for proper termnal differentiation and function of renal tubular epithelia. Binds DNA as a dimer. It can form homodimers or heterodimers with other AP-2 family members. Defects in AP2-beta are the cause of Char syndrome (CHAR) which is characterised by patent ductus anteriosus (PDA), facial dysmorphism and hand anomalies. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Optimal dilution determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degrees C. Aliquot and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T8195-52E2
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
P type: Mab
Isotype: IgG
Purity: Purified by affinity chromatography.
Alternative names: Transcription factor AP2-beta, Activating enhancer-binding protein 2 beta, GENE NAME: TFAP2B
Additional info: Recognizes human AP2-beta.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave