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Transcription Factor AP-2 gamma (TFAP2G, Activating Enhancer Binding Protein 2 gamma, AP2-gamma, hAP-2g, TFAP2C)

Transcription Factor AP-2 gamma (TFAP2G, Activating Enhancer Binding Protein 2 gamma, AP2-gamma, hAP-2g, TFAP2C)

Cat no: T8195-52K

Supplier: United States Biological
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Transcription factor gene AP2-C (AP-2 gamma) belongs to a family of four closely related genes. The AP-2 transcription factor has been shown to play an important role in the development of tissues of ectodermal origin and has also been implicated in mammary oncogenesis (2). A physical and functional association between AP-2gamma transcription factor and the Wwox protein has been demonstrated. results suggest that Wwox tumor suppressor protein inhibits AP-2gamma oncogenic activity by sequestering it in the cytoplasm (2). P-2 gamma had been implicated in multiple functions during proliferation and differentiation based on its expression pattern in trophoblast, neural crest, and ectoderm cells in murine embryos. AP-2 gamma seems to be required in early embryonic development because it regulates the genetic programs controlling proliferation and differentiation of extraembryonic trophectodermal cells (3). Applications: Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:25,000
Catalogue number: T8195-52K
Reactivities: Human
Hosts: Rabbit
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Supernatant
References: 1. Williamson JA, et al. Genomics 35(1): 262-4, 1996. 2. Ageilan RI, et al. Cancer Res 64(22): 8256-61, 2004. 3. Werling U et al. Mol Cell Biol 22(9):3149-56, 2002
Additional info: Recognizes human Transcription Factor AP-2 gamma.

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