Transferrin, Mouse

Transferrin is a single polypeptide chain glycoprotein. It is a member of the iron binding family of proteins. It has a MW of 79.5kD. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration range is 1800-2700mg/L. Serum concentration rises in iron deficiency and pregnancy. Serum concentration falls in iron overload, infection and inflammatory conditions.\n\nApplications: \nSuitable for use as a control or standard in ELISA, Western Blot and conjugation. Other applications have not been tested.\n\nRecommended Dilutions:\nOptimal dilutions to be determined by researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Dilute only prior to immediate use.

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SPECIFICATIONS

Catalog Number

T8205-70

Size

1mg

Form

Supplied as a liquid in sodium phosphate buffer, pH 7.2. No preservative and no stabilizing proteins added. This transferrin is iron-loaded.

Purity

Purified by delipidation, selective precipitation and dialysis. IEP Assay shows a single precipitin arc against anti-mouse transferrin and anti-mouse serum.