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Transforming Growth Factor, beta-1, Recombinant, Human (TGFB1, CED, DPD1, TGFB, TGF-beta-1, Transforming Growth Factor beta 1, Camurati-Engelmann Disease)

Cat no: T8250-13G

Transforming Growth Factor, beta-1, Recombinant, Human (TGFB1, CED, DPD1, TGFB, TGF-beta-1, Transforming Growth Factor beta 1, Camurati-Engelmann Disease)

Human Transforming Growth Factor beta1 (TGF-beta1) is stimulatory for cells of mesenchymal origin and inhibitory for cells of epithelial or neuroectodermal origin. Mature TGF-beta1 is a disulfide-linked homodimer of two chains composed of 112aa residues each. There is a 70% homology between human TGF-beta1 and human TGF-beta2.\n\nBiological Activity: \nThe biological activity of human TGF-beta1 is determined by measuring the acidification of the culture medium (Rat-1 cells) exposed to the growth factor.\n\nStorage and Stability:\nMay be stored at 4 degrees C. For long-term storage, aliquot and store at 4 degrees C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

T8250-13G

Size

5ug

Form

Supplied as a liquid in 5mM HCl, pH 2.5.

Purity

(same/more than) 98% pure by non-reduced SDS gel electrophoresis. Purified by sequential chromatography.

References

1. Ichijo, H., et al., The Journal of Biological Chemistry 266(33): 22,459-22,464 (1994). 2. Yan, Z., et al., The Journal of Biological Chemistry 269(18): 13,231-13,237 (1994).

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