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Transforming Growth Factor beta 1 (Transforming Growth Factor beta-1, TGF-beta-1, Latency-associated Peptide, LAP, TGFB1, TGFB) (PerCP)

Cat no: T8250-16F3


Supplier: United States Biological
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TGF-beta is secreted by cells in the form of an inactive complex. This complex consists of TGF-beta associated non-covalently with a protein designated the latency associated peptide (LAP). TGf-beta and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-beta each consist of a disulfide-linked homodimer and the association of these two components renders TGF-beta inactive and inaccessible to anti-TGF-beta antibodies. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4 degrees C. Freezing PerCP conjugates will result in a substantial loss of activity. PerCP conjugates are sensitive to light.
Catalogue number: T8250-16F3
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Flow Cytometry
Size: 100 tests
Form: Supplied as a liquid in sodium chloride, 0.5% BSA, 0.1% sodium azide. Labeled with Peridinin-Chlorophyll-Protein-Complex (PerCP). Absorption: 482-564nm. Emission: 675nm.
P type: Mab
Isotype: IgG1
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human TGF-beta 1. Species Crossreactivity: mouse.

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