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Transforming Growth Factor Beta 3, Recombinant, Human, Animal Free (Transforming Growth Factor Beta-3, TGF-beta3, AF)

Cat no: 142993

Transforming Growth Factor Beta 3, Recombinant, Human, Animal Free (Transforming Growth Factor Beta-3, TGF-beta3, AF)

The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-b isoforms (TGF-b1, -b2 and -b3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-b3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-b3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis.\n\nSource:\nRecombinant protein corresponding to two 112aa chains from human TGF-b3 expressed in E.coli.\n\nMolecular Weight: \n~25.5kD.\n\nEndotoxin:\n(same/less than)1EU/ug (LAL) \n\nBiological Activity:\nThe activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically <0.05ng/ml.\n\nAA Sequence:\nALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS\n\nStorage and Stability: \nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

142993

Size

2ug

Form

Supplied as a liquid in 20% ethanol, 0.12% acetic acid.

Purity

~98% (Reducing and non-reducing SDS-PAGE).

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