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Transforming Growth Factor beta 3, Recombinant, Mouse (TGFb3)

Cat no: T8250-45L

Transforming Growth Factor beta 3, Recombinant, Mouse (TGFb3)

Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.\n\nTGF-b3 Mouse Recombinant produced in E. coli is a disulfide-linked homodimeric, non-glycosylated, polypeptide chain containing 112 amino acids and having a molecular mass of 25,445 Dalton. \n\nThe sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Asp-Thr-Asn.\n\nBiological Activity: The ED50 as determined by the cell toxicity assay using the WHO Standard 98/608 as a direct comparison is < 0.05ng/ml corresponding to a specific activity of 20,000,000 Units/mg.\n\nStorage and Stability:\nMay be stored at 4 degrees C. For long-term storage, aliquot and store at 4 degrees C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.\n\n\n\n

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SPECIFICATIONS

Catalog Number

T8250-45L

Size

10ug

Form

Supplied as a liquid in 20% ethanol and 0.12% acetic acid.

Purity

(same/more than)98% (SDS-PAGE)

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