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Trefoil Factor 1, Recombinant, Human, aa25-84, His-tag (Tff1, Bcei, Ps2, Protein pS2)

Cat no: T8269-73D

Trefoil Factor 1, Recombinant, Human, aa25-84, His-tag (Tff1, Bcei, Ps2, Protein pS2)

TFF1 (Trefoil factor 1) is member of trefoil family, characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. TFF1 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. Purified by using conventional chromatography techniques.\n\nSource:\nRecombinant corresponding to aa25-84 of human TFF1, fused to His-tag at N-terminal, expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MEAQTETCTV APRERQNCGF PGVTPSQCAN KGCCFDDTVR GVPWCFYPNT IDVPPEEECE F\n\nMolecular Weight: \n~9kD (81aa), confirmed by MALDI-TOF\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

T8269-73D

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8, 1mM DTT, 100mM sodium chloride, 0.1mM PMSF, 20% glycerol.

Purity

~90% (SDS-PAGE)

References

May FE., et al. (1997). J. Pathol. 183:4-7. Gott P, et al. (1997). Eur J Hum Genet 4(6):308

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