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TREM-1 (Triggering Receptor Expressed on Monocytes 1, Triggering Receptor Expressed on Myeloid Cells 1 Precursor) (PE)

Cat no: T8282-09B

TREM-1 (Triggering Receptor Expressed on Monocytes 1, Triggering Receptor Expressed on Myeloid Cells 1 Precursor) (PE)

TREM-1 stimulates neutrophils and monocytes-mediated inflammatory responses. TREM-1 activation, together with LPS and other PRR ligands, amplifies the production pro-inflammatory cytokines and thus the inflammatory response. The TREM-1 pathway also plays a crucial role in septic shock. Clone has been shown to activate monocytes and granulocytes.\n\nApplications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: Neat 20ul labels 1x10e6 cells in 100ul.\nOptimal dilutions to be determined by the researcher.\n\nRecommended Negative Controls:\nMouse IgG1 Negative Control (PE)\nMouse IgG1 Negative Control (PE) \n\nStorage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid for 6 months. Dilute only prior to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.

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SPECIFICATIONS

Catalog Number

T8282-09B

Size

25Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 0.2% BSA.

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG1

Additional Info

Recognizes triggering receptor expressed on myeloid cells 1 (TREM-1), a receptor expressed on CD14+ monocytes, macrophages and neutrophils. It is also highly expressed in inflammatory lesions caused by fungi and bacteria.

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