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TREM-1 (Triggering Receptor Expressed on Monocytes 1, Triggering Receptor Expressed on Myeloid Cells 1 Precursor)

TREM-1 (Triggering Receptor Expressed on Monocytes 1, Triggering Receptor Expressed on Myeloid Cells 1 Precursor)

Cat no: T8282-09C

Supplier: United States Biological
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TREM-1 stimulates neutrophils and monocytes-mediated inflammatory responses. TREM-1 activation, together with LPS and other PRR ligands, amplifies the production pro-inflammatory cytokines and thus the inflammatory response. The TREM-1 pathway also plays a crucial role in septic shock. Clone has been shown to activate monocytes and granulocytes. Applications: Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:5-1:10 10ul labels 1x10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies Goat Anti Mouse IgG IgA IgM lk. Phos., HRP HuCAL Anti Mouse IgG1HRP Sheep Anti Mouse IgG (H&L) Biotin, FITC Goat Anti Mouse IgG (H&L) Alk. Phos., DyLight(TM)488, DyLight(TM)549, DyLight(TM)649, FITC, HRP Rabbit Anti Mouse IgG RPE Goat Anti Mouse IgG (Fc) FITC, HRP Rabbit Anti Mouse IgG HRP Goat Anti Mouse IgG FITC Goat Anti Mouse IgG RPE Goat Anti Mouse IgG HRP Rabbit Anti Mouse IgG FITC Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8282-09C
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Western Blot
Size: 25ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes triggering receptor expressed on myeloid cells 1 (TREM-1), a receptor expressed on CD14+ monocytes, macrophages and neutrophils. It is also highly expressed in inflammatory lesions caused by fungi and bacteria.

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