TREM1, Recombinant, Human, aa21-205, His-Tag (Triggering Receptor Expressed On Myeloid Cells 1, CD354, TREM-1)

TREM1 is a receptor belonging to the Ig super family that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. \n\nSource:\nRecombinant protein corresponding to aa21-205 from human TREM1 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~23.3kD (209aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSM LEDYHDHGLL RVRMVNLQVE DSGLYQCVIY QPPKEPHMLF DRIRLVVTKG FSGTPGSNEN STQNVYKIPP TTTKALCPLY TSPRTVTQAP ATKLTE EKYELKEGQT LDVKCDYTLE KFASSQKAWQ IIRDGEMPKT LACTERPSKN SHPVQVGRII PKSTADVSTP DSEINLTNVT DIIRVPVFN\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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