Home  >  Products  >  TREML1 (TREM-like transcript 1, OTTHUMP00000017858, dJ238O23.3, TLT1, TLT-1, PRO3438, MGC119173, GLTL1825, triggering receptor expressed on myeloid cells-like 1)
TREML1 (TREM-like transcript 1, OTTHUMP00000017858, dJ238O23.3, TLT1, TLT-1, PRO3438, MGC119173, GLTL1825, triggering receptor expressed on myeloid cells-like 1)

TREML1 (TREM-like transcript 1, OTTHUMP00000017858, dJ238O23.3, TLT1, TLT-1, PRO3438, MGC119173, GLTL1825, triggering receptor expressed on myeloid cells-like 1)

Cat no: T8282-38A

Supplier: United States Biological
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TREML1 is a type I transmembrane protein that differs from TREM in the cytoplasmic region by having two ITIMs (Immunoreceptor Tyrosine-based Inhibition Motif). A splice variant lacking ITIMs in its cytoplasmic domain also exists. TREML1 is found only in platelets and megakaryocytes. The extracellular region of human and mouse TLT-1 share 75% amino acid sequence identity. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:2000 Western Blot: 0.3-1ug/ml detects ~30kDa band observed in Human Bone Marrow lysates (calculated MW of 32.7kDa according to NP_835468.1). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8282-38A
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Nurden AT, Nurden P, Bermejo E, Combri
Additional info: Recognizes human TREML1.

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