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TREML2 (Triggering Receptor Expressed on Monocytes-Like Protein 2, TREM-Like Transcript 2, TLT-2)

Cat no: T8282-40

TREML2 (Triggering Receptor Expressed on Monocytes-Like Protein 2, TREM-Like Transcript 2, TLT-2)

TREML2, also known as TLT2 (TREM-like transcript 2), is a transmembrane protein in the TREM family of immunoregulatory molecules. TREML2 contains one Ig-like V-type domain and a Ser-Thr rich region. Unlike other TREM proteins, TREML2 lacks cytoplasmic ITIM and ITAM motifs and a DAP12-interacting transmembrane segment. TREML2 is expressed throughout the B cell lineage, and it is upregulated in neutrophils and macrophages in response to inflammatory stimuli. The extracellular regions of human and mouse TREML2 share 54% amino acid sequence identity.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications have not been tested.\n\nRecommended Dilution:\nDirect ELISA: 0.5-1.0ug/ml. Detection limit for rhTREML2 is ~2.0 ng/well. \nWestern Blot: 0.1-0.2ug/ml. Detection limit for rhTREML2 is ~25 ng/lane under non-reducing and reducing conditions. \nOptimal dilutions should be determined researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile PBS with 40-50% glycerol and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

T8282-40

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with 0.5ml sterile PBS, 40-50% glycerol.

P Type

Pab

Purity

Purified by affinity chromatography.

Isotype

IgG

Additional Info

Recognizes human TREML2. Less than 1% crossreactivity with rhTREML1.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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