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Treponema pallidum TmpA, Recombinant (Syphilis)

Cat no: T8300-50

Treponema pallidum TmpA, Recombinant (Syphilis)

Treponema pallidum is the causative agent of syphilis. It is a spirochete, a helical to sinusoidal bacterium with outer and cytoplasmic membranes, a thin peptidoglycan layer, and periplasmic flagella. Mechanisms of T. pallidum pathogenesis are poorly understood. No known virulence factors have been identified, and the outer membrane is mostly lipid with a paucity of proteins. Consequently, existing diagnostic tests for syphilus are suboptimal, and no vaccine against T. pallidum is available. TIGR sequenced the genome of T. pallidum subsp. pallidum (strain Nichols) by the whole genome random sequencing method. The T. pallidum genome is a circular chromosome of 1,138,006 base pairs containing a total of 1041 predicted open reading frames.\n\nFull length recombinant protein produced from beta-galactosidase (114kDa) fused at the N-terminus. Reacts strongly with human Treponema pallidum-positive serum.

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SPECIFICATIONS

Catalog Number

T8300-50

Size

100ug

Form

Supplied as a liquid in 8M urea, 20mM Tris HCl, pH 8.0, 10mM 2ME.

Purity

(same/more than) 95% (SDS-PAGE, 280 nm, Bradford)

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