Triamcinolone Acetonide (Adcortyl, Azmacort, Delphicort, Extracort, Ftorocort, Kenacort-A, Tramacin, Triam, Tricinolon, Vetalog, Volon A, Volonimat)

Triamcinolone Acetonide is a more potent type of triamcinolone (synthetic corticosteroid), being about 8 times as effective as prednisone. It is used to treat medical conditions, such as eczema, psoriasis, arthritis, allergies, ulcerative colitis, lupus, sympathetic ophthalmia, temporal arteritis, uveitis, and ocular inflammation, visualization during vitrectomy and the prevention of asthma attacks. Triamcinolone Acetonide has an elimination half-life of 1.5-2.5 hours in Humans [1]. 6 beta hydroxlated and 21-carboxylated metabolites have been reported in humans, rats and dogs for triamcinolone acetonide [1,2]. little or no parent compount was detected in plasma 24 hours after oral administration in humans[2]. plasma binding in humans was 68% [2]. Triamcinolone was not a major metabolite of triamcinolone acetonide in humans, only about 1% of the dose was found in the urine as triamcinolone [3]. 6 beta-H+ydroxytriamcinolone acetonide was the major matabolite in urine of rats, dogs and humans after intra-venous and intra-muscular administration. Hydrolytic cleavage of the acetonide group did not appear to be significant[4].\n\nApplications:\nSuitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry, Immunoassays, development of rapid tests and other antibody recognition assays. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

T8328-10A

Size

100ug

Applications

ELISA, IHC, WB

Hosts

Sheep

Form

Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by ammonium sulfate precipitation.

Isotype

IgG

References

1. Rx List Allernaze. (0712/i/0001). 2. Argenti D, Jensen BK, Hensel R, Bordeaux K, Schleimer R, Bickel C, Heald D. (2000) A mass balance study to evaluate the biotransformation and excretion of (14C)- triamcinolone acetonide following oral administration. J Clin Pharmacol.; 40(7):770-80. PMID: 10883419. (0712/lr/0001). 3. M

Additional Info

Recognizes triamcinolone acetonide.